Welcome to MUCalc 4.0

A Measurement Uncertainty Calculator for Chemical Analysis

MuCalc 4.0 implements the Bottom-Up method for measurement uncertainty calculations for chemical analysis. It can calculate measurement uncertainty for one or more of the components Homogeneity, Calibration Standards, Sample Preparation, Calibration Curve and Method Precision by uploading the required data for the component. It also calculates the combined uncertainty for the components where data has been uploaded.

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Homogeneity

Sample Preparation

Calibration Standards

Calibration Curve

Method Precision

Combined Uncertainty

Help & References

References

Klu et al. 2021. Joyce K. Klu, Jane A. Officer, Alexandra Park, Roy Mudie, Niamh NicDaeid, Measurement uncertainty in quantifying delta-9-tetrahydrocannabinol (THC) in blood using SPE and LC/MS/MS, Forensic Science International, Volume 322, 110744, ISSN 0379-0738, https://doi.org/10.1016/j.forsciint.2021.110744.

Klu et al. 2025. Joyce K. Klu, Roberto Puch-Solis, Roy Mudie, Victoria Marland, Niamh Nic Daeid, Open-access Measurement Uncertainty Calculator MUCalc and its application to the quantification of Etizolam in tablets using High-Performance Liquid Chromatography (HPLC), Science & Justice, Volume 65, Issue 1, 2025, Pages 70-81, ISSN 1355-0306, https://doi.org/10.1016/j.scijus.2024.11.001.

Manual

View the MUCalc Manual

Download the MUCalc Manual

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